高血压病肾气亏虚证“病机—证候—方药”体系的构建及其临床依据的系统评价.pdf

Construction of Pathogenesis-Symptom-Treatment System and the systematic review of clinical evidence for the Kidney-qi Deficiency Syndrome in Hypertension Speciality: Clinical study on the treatment of heart system disease with Traditional Chinese Medicine Author: Shi min Tutor: Prof.Zhang Yunhui Abstract Objective: To arrange the relevant ancient literatures, construct Pathogenesis-signs-agent system, and evaluate the efficacy and safety of Invigorating Kidney-qi Therapy for the Kidney-qi Deficiency Syndrome in Hypertension. Method: 1. Through the arranging of the ancient literature and deep excavation analysis of the various periods of the major essays and physician views, analyze the progress of medical thoughts and unique feature.Its contents related to kidney deficiency syndrome, etiology, pathogenesis, symptoms, diagnosis, treatment, medication characteristics, and prevention of nursing.Establish perfect Pathogenesis-signs-agent system. 2. Retrieve the literatures of randomized controlled trials(RCT) published on the biological medical journals between 1989 and 2010 about Invigorating Kidney-qi Therapy for the Kidney-qi Deficiency Syndrome in Hypertension, select the eligible researches, and use RevMan software to analyse the results of Heterogeneity test, Meta-analysis, Funnel analysis, Sensitivity analysis.3.Analysis related records ,discuss the clinical efficacy of Invigorating Kidney-qi Therapy. Results: 1. Extensive collection of ancient literature, and successfully constructed the Pathogenesis-signs-agent of the system, provide a useful reference for the clinical treatment.2.5 RCTs were included, the Jadad grading of all studies are lo