茶多糖铁复合物对缺铁性贫血大鼠补铁效果研究唐敏敏.pdfVIP

26 2 2009 3 Vol. 26 No. 2 Stu ies of Trace Elements an Healt h Mar. 2009 茶多糖铁复合物对缺铁性贫血大鼠补铁效果研究 1 1 1 1 2 3 , , , , , Buchili Petter 1. 中国海洋大学食品科学与工程学院, 山东 青岛 260003; 2. 青岛海洋地质研究所, 青岛 266071; 3. 雀巢研发中心上海有限公司, 上海201812 : 以不同剂量 以铁计 1座机电话号码 mg/ kg iet 的茶多糖铁复合物 TPS Fe 作为补铁剂对缺铁性贫血 大鼠进行补铁试验, 测定大鼠体 变化血红蛋白含量和肝脏中几种金属元素含量, 考察不同剂量TPS Fe 对大鼠早期生长铁利用, 以及对肝脏中金属离子的影响结果表明, 以硫酸亚铁 FeSO 生物利用率为 4 100% 时, TPS Fe 的铁相对生物利用率在 102% ~ 110% 之间; TPS Fe 和FeSO 补铁组21 补铁期内的平 4 均生物利用率存在极显著性差异; TPS Fe 补铁组的体 增长率随给药量的增加而增加, 其中3648 mg/ kg iet 剂量组相对阴性对照组差异极显著, 且该剂量组肝脏储存铁达到正常水平, 肝脏铜锌比降低到正常水平 : 多糖; 铁; 复合物; 生物利用度 + : O614. 81 1 : A : 1005- 5320 2009 02- 0004- 04 Effect of Tea polysaccharide- Iron complex TPS Fe Supplementation on Biological Utilization of Iron of Wistar ats 1 1 1 TANG Min- min , WANG Dong- feng , HOU Yang- feng , et al 1. Food Science and Technology College of Ocean University of China, Qingdao 260003; 2. QingdaoInstitute of Marine Geology, Qingdao 266071; 3. estle RD Shanghai, Shanghai 201812, China Abstract: The experiment was con ucte to investigate the effect of tea polysacchari e- iron complex TPS Fe supplementation 12, 24, 36, 48 mg/ kg iet on rats of Fe eficiency at growth, biological value of iron, an contents of metal ions in liver. The weight gaine , an bloo hemoglobin Hb was measure every 7 in the first 21 ays. On the 22n ay, all the rats were kille an then the content of iron in liver of rats w as measure respectively. The results show that the relative bioavailability of Hb was 102% ~ 110% for T PS Fe to FeSO after the Fe supplemente iet; There was an significant ifference between TPS Fe an FeSO group in the 4 4 average RBV; The a e w eight rates of the fourgroups supplemente with TPS Fe increase with the content of TPS Fe, an the 36, 48 mg/ kg iet groups ha significant ifferences compare with negative control group, an the iron storage a e an the value of Cu/ Zn increase to normal level respecti