三种治疗方案对强直性脊柱炎证型的干预的研究.pdf

IgA、方案一对IgG具有统计学差异（P＜0.05）；方案三与方案一对BASDAI评分和 PGA评分均具有统计学差异（P＜0.05）；方案三对指地距改善具有统计学差异 P0.05）。在肾虚督空证中，方案一对炎性指标具有统计学差异（P＜0.05）；三种 （ 方案对BASDAI评分、PGA评分改善具有有统计学差异（P＜0.05），三种治疗方案对 体格检查具有统计学差异（P＜0.05）。在肝肾两虚证中，方案一对血沉具有统计学差 异（P＜0.05）；方案二对Ig有统计学差异（P＜0.05），三种方案对IgA具统计学差 异（P＜0.05）。 结论：方案一对肾虚督空证的炎性指标、体格检查（指地距、枕墙距、Schober、 胸廓扩张度）、对湿热痹阻证、寒湿痹阻证、瘀血痹阻证的IgG、对BASDAI和PGA评 分效佳。 方案二对湿热痹阻证、寒湿痹阻证、瘀血痹阻证IgM；肾虚督空证的体格检查（指 地距、枕墙距、Schober、胸廓扩张度）；湿热痹阻证、寒湿痹阻证、肝肾两虚证的 BASDAI和PGA评分效佳。 方案三对湿热痹阻证的炎性指标，免疫球蛋白、指地距、枕墙距、Schober、胸 廓扩张度以及Bath评分和自我评价均明显改善。 关键词 强直性脊柱炎；中医证型；治疗方案；干预研究 Intervention research of the three therapeutic schemes on the ankylosing spondylitis syndromes Speciality: Integrated Traditional Chinese Medicine and Western Medicine Author: Jiakaijun Tutor: Professor Liu Ying ABSTRACT Object: The purpose of the paper is to observe the clinical efficacy of the different syndromes of three different treatment programs on ankylosing spondylitis , to analyze what kind of treatment programs is the best and to provide a reliable basis for the treatment of ankylosing spondylitis . Methods: This study reviews and observes 75 cases of AS patients who were devided into five types of syndromes in traditional Chinese medicine. Through the main observations which include finger-ground distance, the pillow wall distance, Schober test, thoracic activity,erythrocyte sedimentation rate, C-reactive protein,Ig,active and inactive period ,the BASDAI scores and PGA scores ,we can study the relationship with TCM syndromes. Three clinical treatment programs: 1.Voltaren + kidney Juanbi pill;2. Voltaren + sulfasalazine; 3.Voltaren + tumor necrosis factor receptor antibody fusion protein (etanercept).The patients of each type of TCM