Three-dimensional+conformal+radiotherapy+plus+concurrent+DICE+chemotherapy+for+early-stage+nasal-type+natural+killer-T-cell+lymphoma+of+Waldeyer’s+ring：A+single-institution+study.pdfVIP

Oncology and Translational Medicine August 2015, Vol. 1, No. 4, P181–185 DOI 10.1007/s10330-015-0051-6 ORIGINAL ARTICLE Three-dimensional conformal radiotherapy plus concurrent DICE chemotherapy for early-stage nasal-type natural killer/T-cell lymphoma of Waldeyer’s ring: A single-institution study* 1 2 2 2 2 2 2 Ji Zhou , Daiyuan Ma , Yeqin Zhou , Xianfu Li , Bangxian Tan , Mi Liu , Tao Ren () 1  Department of ENT, The Affiliated Hospital, North Sichuan Medical College, Nanchong 637007, China 2  Department of Oncology, The Affiliated Hospital, North Sichuan Medical College, Nanchong 637007, China Abstract Objective  Nasal-type natural killer/T-cell lymphoma of Waldeyer’s ring (WR-NK/TL) has different clinico- pathological characteristics from those of other subtypes of NK/T lymphoma; thus, the optimal treatment remains unclear. To find a more effective treatment model for WR-NK/TL, we conducted a single-center study of concurrent radiochemotherapy. Methods  Forty-five patients with newly diagnosed stage IE to IIE WR-NKTL were randomly divided into two groups. The 23 cases in the concurrent radiochemotherapy group were treated with three-dimensional conformal radiotherapy (48–52 Gy) and 2 courses of DICE (dexamethasone, ifosfamide, cisplatin, and etoposide) synchronous chemotherapy. The 22 cases in the radiotherapy