Racialethnic standards for fetal growth the NICHD Fetal Growth Studies》.pdf

Report of Major Impact Racial/ethnic standards for fetal growth: the NICHD Fetal Growth Studies Germaine M. Buck Louis, PhD, MS; Jagteshwar Grewal, PhD, MPH; Paul S. Albert, PhD; Anthony Sciscione, DO; Deborah A. Wing, MD; William A. Grobman, MD, MBA; Roger B. Newman, MD; Ronald Wapner, MD; Mary E. D’Alton, MD; Daniel Skupski, MD; Michael P. Nageotte, MD; Angela C. Ranzini, MD; John Owen, MD, MSPH; Edward K. Chien, MD; Sabrina Craigo, MD; Mary L. Hediger, PhD; Sungduk Kim, PhD; Cuilin Zhang, MD, MPH, PhD; Katherine L. Grantz, MD, MS OBJECTIVE: Fetal growth is associated with long-term health yet no cubic splines. Estimated fetal weight (EFW) and biometric parameter appropriate standards exist for the early identification of undergrown percentiles (5th, 50th, 95th) were determined for each gestational or overgrown fetuses. We sought to develop contemporary fetal growth week and comparisons made by race/ethnicity, with and without standards for 4 self-identified US racial/ethnic groups. adjustment for maternal and sociodemographic factors. STUDY DESIGN: We recruited for prospective follow-up 2334 healthy RESULTS: EFW differed significantly by race/ethnicity 20 weeks. Spe- women with low-risk, singleton pregnancies from 12 community and cifically at 39 weeks, the 5th, 50th, and 95th percentiles were 2790, perinatal centers from July 2009 through January 2013. The cohort 3505, and 4402 g for white; 2633, 3336, and 4226 g for Hispanic; 2621, comprised: 614 (26%) non-Hispanic whites, 611 (26%) non-Hispanic 3270, and 4078 g for Asian; and 2622, 3260, and 4053 g for black blacks, 649 (28%) Hispanics, and 460 (20%) Asians. Women were women (adjusted global P .001). For individu