Regional homogeneity of spontaneous brain activity in adult patients with obsessive–compulsive disorder before and after cognitive behavioural therapy》.pdf
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Regional homogeneity of spontaneous brain activity in adult patients with obsessive–compulsive disorder before and after cognitive behavioural therapy》.pdf
Journal of Affective Disorders 188 (2015) 243 –251
Contents lists available at ScienceDirect
Journal of Affective Disorders
journal homepage: /locate/jad
Regional homogeneity of spontaneous brain activity in adult patients
with obsessive–compulsive disorder before and after cognitive
behavioural therapy
Xiang-Yun Yang a, Jing Sun a,c, Jia Luo a, Zhao-Xi Zhong a,1, Ping Li b, Shu-Min Yao a,
Hong-Fang Xiong a, Fang-Fang Huang a, Zhan-Jiang Li a,n
a Department of Clinical Psychology, Beijing Key Lab of Mental Disorders, Beijing Anding Hospital, Capital Medical University, and Center of Schizophrenia,
Beijing Institute for Brain Disorders, Beijing, People ’s Republic of China
b Department of Psychiatry, Qiqihaer Medical University, Qiqihaer, Heilongjiang, People ’s Republic of China
c Menzies Health Institute Queensland and School of Medicine, Griffi th University, Australia
a r t i c l e i n f o a b s t r a c t
Article history: Background: Cognitive behavioural therapy (CBT) is an effective treatment for obsessive–compulsive
Received 28 May 2015 disorder (OCD). Several neuroimaging studies have explored alterations of brain function in OCD patients
Received in revised form as they performed tasks after CBT. However, the effects of CBT on the neural activityin OCD during rest
16 July 2015 remain unknown. Therefore, we investigated changes in regional homogeneity (ReHo) in OCD patients
Accepted 30 July 2015
before and after CBT.
Available online 28 August
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