凉血消斑汤合三粉对特发性血小板减少性紫癜模型小鼠造血系统及其TNFα、IL4的影响.pdfVIP

T h e O b serv a tio n o f H em a to P o ietie sy stem 、 IL 一4 a n d T N F 一a L ev els o f Id io P a th ic T h ro m b o cy to P en ie P u rp u ra M o u se Tr ea ted B y L ia n g x u ex ia o b a n a n d sa n fen F o rm u la S P eeia lity :In tem alM ediein e of lntegrated T C M an d w 亡Stem M ed iein e A u th er :C h e 、妞n li Tu to r :P ro f.X u R u iro n g A b str a C t O bjectiv e : To observe the effe et of L iangxuex iaoban and sanfen F orm u la to the P latelet eoun t，b leed in g tim e ，M eg ak ary o cyte eells an d the lev el o f l，N F 一a an d IL 一4 in P er iP h era l b lo o d serum o f IT P m iee . M eth o d s : U sin g th e imm un e m o d e lin g m eth o d o f iniraPeritoneal injeetion of eavy一anti一m ou se Platelet se~ (A P S) to estab lish B A L B /C m iee w ith IT P，L ian gX u ex iaoban an d san fen F orm u la hav e researeh ed eon1P arin g w ith W 亡ix u en in g P art ie le s a s the P o sitiv e eo n tro l gro uP to o b serv e th e eh an g e s in th e se in d ieato rs. R esu lts : T h e P late lets eo u n t wa s o b v io u sly ra ised ， b leed in g tim e w a s d eeurt ation ，m arr ow m eg ak ary oeyte wa s d ecrea sed 田ld P ro du ein g P latelets m egak ary o cyte w a s m u ltiP lieatio n ，th e lev els o f sermu IN F 一a an d IL 一4 w ere a seen d ed in fee d in g L ian g x u ex iao b an an d san fen F o rm u la . C o m P arin g w ith m o d e l，there w ere sig n ifiean t dev iation (P 0 .05). C on clu sion : T h e L iangxuex iaoban and san fen F orm u la has the fun ctio n to in erea se IT P m o d e l m o u se P late lets eo u llt，to sh o rten th e b le ed in g tim e ，to P rom ote th e m