《Nd(Ⅲ),Ce(Ⅲ)与5#39;-IMP配合物的合成及抗菌作用研究》.pdfVIP

第35卷第1期 稀 有 金 属 2011年1月 METALS VoL35N0-l CHINESEJOURNALOFRARE Jan．2011 陈燕青+，丁德润，唐博合金，张晓露，孙玉清 (上海工程技术大学化学化工学院，上海201600) TA滴定确定了配合物的组成，并通过摩尔电导、IR、Uv、TG—DSC的测定对配合物进行了表征。结果表明5’·次黄嘌呤核苷酸以嘌呤碱基上的 进行比较，结果表明两种配合物对金黄色葡萄球菌和肺炎球菌均有强抑制作用，而配体5’一IMP无抑菌作用。 关键词：5-次黄嘌呤核苷酸；配合物；抑菌性；稀土 doi：10．3969／j．issn．0258—7076．2011．01．028 中图分类号：0641．4文献标识码：A 文章编号：0258—7076(2011)01—0155一04 andAnti-Bacterialof of 5-IMP Synthesis ActivityComplexesNd(m)，Ce(m)啊th Chen Yanqing’，DingDerun，TangBohejin，ZhangXiaolu，SunYuqing and Chemical Engineering，Shanghai 201600，China) (CollegeofChemistry Uni∞rsityofEngineeringScience，Shanghai Abstract：Two龇earth Inosine disodium complexesRE(m)一IMP(RE=Nd3+，Ce3+)with5-1-monophosphatesalt(5-IMP) were weredeterminedelementalandEDTAtitration wagalsocharacterized compositions by analysis analysis．It by synthesized．The andTG—DSC．Theresultsshowedthatthe baseofinosine coordinatewith ce- IR．UV purine 5’一1-monophosphate neodymium(Ⅲ)and 7-Natom．The didnotcoordinatedwith Wasinteraction rium(11I)troughphosphategroup neodymium(11I)andcerium(Ⅲ)．There foundthat between theantibacterialbetweenthe 5-IMPandtwosolid Was comparing activity ligand complexes，it phosphategroup．By boththe exhibitedexcellentantibacterial aureusand the 5-IMPhad abilityagainst pneumococcus，butligand complexes staphylococcus ant