电喷雾质谱应用于手性联萘酚醛型主体分子对氨基酸及氨基醇地手性识别研究.pdf

MASTER’SAAcademicNormalAcidsAlcoholsAminoAminoTHESISBinol-BasedHost-GuestPartialForProfessorThesisChenFulfillmentCentralChinaZuoChiralChiralESI·-MSofandSubmittedofofthetheininin MASTER’STHESIS1 MASTER’STHESIS workwaswithwaswerewerewerewerewerewaterwerewewerewewithwithMASTER’SAsWaSWasM+1AbstractMassmolecularmixedmademethotism-CPBAm—CPBAmethodsmoremoremixedmassmechanism．InD-aminobinol-basedunstableunstableunstableunstableunstablebeenusedTHESISDMSOhostshoStshostshasaaleanewreactionsreactedreactionRFL—aminokindsrelativeresearchChilalresultsRFrelativerelativeresultrelmivenewreactionbetweenbetweenorESI-MS．ForreactionratereactionreactionreactionskindscornnlorlacidsandalcoholsSHandaminoandSHandSHandaminoacidsaminoandandanlinoalmostaminoalcoholsandofofofofofofofofofofofofofofofofofofobviousofofofoxidationofaminoaminoacidsasaminoaminoasaminoacidsassemblecontentstototototheformedforforfactorsacidsandacidsandandacidsalcohols．andachievesalnedividedchiralcontrolledchiraldifferencechiralchiraldissolvedchitaldetectedconditionchiraldidn’tchiralcontrolledcontrolformedforthistwothethetwothethethethanthethanthethethethethisthatthe2．nleIIdeuteratedstructureformedtheirthethethethethethethethethethanthethethetheenvironmentthethetransformationstablestablestablestudiedsolventsstudiedselectivetwotwoIonizationledintoinisilllineinfluencedinilnineinimineintoinstudied111e1．Our1imineimineininimine waswaswerewerewhichMASTER’SmoremassunderTHESISundernothaveasreactionnerolachieveandofofobtainedofoxidatedofalmostofobtained．toalcoholscertainconditionthethanthisthethechemoselectiveconditionenvironmentto111solventsionization MASTER’SAbstractTHESIS—lII1．3．116 MASTER’STHESIS436053 MASTER’STHESIS MASTER’STHESIS2 硕士学位论丈 ⑨MASTER’STHESIS [71。由此可见，手性识别对于指导手性化合物的合成具有重大的意义。 在分子材料研究领域，手性也扮演者十分重要的角色。手性液晶材料由于其分 子结构包含一个或多个手性碳原子而形成扭曲的螺旋结构，从而具有与众不同的光 学性能，因此研究构成液晶材料分子的立体结构，对于新型液晶材料的发展有着非 常重要的意义毕～01。另外，由手性单体聚合而成的手性高分子材料和对应的外消旋 或非手性单体聚合物相比较，它们的熔点、光学性能及力学性能等都有很大的差异。 总之，对手性化合物进行手性识别，