Noninvasive Measurement of Liver Fibrosis by Transient Elastography and Influencing Factors in Patients with Chronic Hepatitis B―A Single Center Retrospective Study of 466 Patients.pdfVIP

J Huazhong Univ Sc i Te chnol ［Me d Sc i ］ D OI 10.1007/s11596-0 12-00 12-z 32( 1) :69-74,20 12 69 J Huazhong Univ Sc i Te chnol ［Med Sci ］ 32(1) :2012 Non invasive Measure ent of Liver Fibr osis by Tr an sient Elastogr aphy an d In flu en cin g F act or s in P atients wit h Chr on ic * Hep atitis B ―A Single Center Ret r osp ective Stu dy of 466 P at ients † † Hongfang DIN G (丁红芳) , Ting WU (吴 婷) , Ke MA (马 科), Xiaojing WANG (王晓晶), Zegu ang WU (武泽光), Wei GUO (郭 威), Junying QI (齐俊英), Qin NIN G (宁 琴)# Dep ar t ent of In fectious Diseases, Tongj i Hospita l, Tongj i Medica l College, Hua zhong University of Scien ce and Techn ology, Wuh an 430030, Chin a ©Hu azhong University of Science and Technology and Springer-Verlag Berlin Heidelberg 20 11 Su ar y : Th e noninv asive easure ent of liver stiffness (L S) was evaluated by transient elastogra- phy (FibroScan) and the p ossible influencing factors fro the patients ’clinical situations including age, gender, liver in fla ation represented by alanine tran sa inase (ALT) and total b illirub in (TBIL) lev el, HBV rep lication (HBV DNA loads), p ortal v ein pressure (portal v essel dia eter, PVD), splenic thick - ness (SPT) and body ass index (BMI) were an alyzed in p atient s with chronic h epatitis B (CHB). A to- tal of 466 p atient s in clu ding 31 p atient s with acute-on -c hronic liver failure (A CLF), and 435 patients