Mitral peak early diastolic filling velocity to deceleration time ratio as a predictor of prognosis in patients with chronic heart failure and preserved or reduced ejection fraction.pdfVIP

JournalofGeriatricCardiology(2015)12：346-352 ~2015JGCAllrightsreserved；www．jgc301．tom ■ · OpenAccess。 M itralpeakearlydiastolicfillingvelocitytodecelerationtimeratioasa predictorofprognosisinpatientswithchronicheartfailureandpreserved orreducedejectionfraction FloraPirozzi，AntoneUaPaglia，LauraSasso，PasqualeAbete，AngeloCarlomagno，CarloGTocchetti， DomenicoBonaduce，MarioPetretta DepartmentofTranslationalMedicalSciences，SectionofInternalMedicine,Federico1IUniversity,Naples，肋 Abstract objec心 Dopplerderivedmitralpeakearlydiastolicfiningvelocitytodecelerationtimeratio(F_CDT)hasbeenproposedasparameterfor predictingprognosisingeneralpopulation．TI1isstudyprospectivelyinvestigatestheincrementalprognosticvalueofE／DToverclinica1．conven- tionaleehocardiographicandmilral-Dopplervariablesinpatientshospitalizedfordecompensatedheartfailure(}玎)．Methods Weanalyzed95 HFpa~nets(meanage64．8士12．2years)hospitalizedatourinstitutionfromJanuary2010toMarch2012．nIeprimaryend-ponitwascardiac deathorhospitaliTation,whicheveroccurredfirst．Coxregressionanalysiswasperformedot identifysignificantpredicotrsofoutcomes．Results Duringfollow-up(median37．7months)13patinetsdidenad44werehospitalizedforacardiacevent．Atunivariableanalysis，NewYorkHeart Association(NVHA)functionalclass，furosemidedosage,lateraltricuspidalannularplanesystolicexcursion,decelerationlimenadED／Twere predictiveofoutcome．Atmultivariableanalysis，E／DTwastheonlypredicotrofprognosis(hazardratio=1．02，P：0．018)，#ringnicremnetal prongosticinformationtoclinicalnadotherechocardio-graphicmeasures(globalchi-squarefrom 15．4ot25．2：P 0．032)．Conclusions B，DT givesindependnetandnicremnetalprongosticinformationniHFpatinets． JGeriatrCardiol2015；12：34-6352．doi：10．11909~．issn．1671-5411．2015．04．006 Keywords：Echocardiographiceva