Real time monitoring of bioreactor mAb IgG3 cell culture process dynamics via Fourier transform infrared spectroscopy： Implications for enabling cell culture process analytical technology.pdfVIP

Front．Chem．Sci．Eng．2015，9(3)：386-406 D0I10．1007／sl1705—015—1533—3 RealtimemonitoringofbioreactormAbIgG3cellculture processdynamicsviaFouriertransform infrared spectr0sc0py：Implicationsforenablingcellcultureprocess analyticaltechnolo Huiquanwu(函) ，ErikRead3，MauryWhite，BrittanyChavez3，KurtBrorson3，CyrusAgarabi， M ansoorKhan lDivisionofProductQualityResearch(DPQR，HFD一940)，0街ceofTestingandRese~ch(OTR)，OfficeofPharmaceuticalQuality(OPQ)，Center f0rDrugEvaluationandResearch(CDER)，USFood