Lack of Effect of the Salmonella Deubiquitinase SseL on the NF-κB Pathway.PDFVIP

Lack of Effect of the Salmonella Deubiquitinase SseL on the NF-kB Pathway Francisco S. Mesquita, David W. Holden, Nathalie Rolhion* Section of Microbiology, MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom Abstract Intracellular replication of Salmonella enterica requires effector proteins translocated across the Salmonella-containing vacuolar membrane by Salmonella pathogenicity island-2 (SPI-2) encoded type III secretion system (T3SS). The SPI-2 T3SS effector SseL is a deubiquitinase that contr