Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.PDFVIP

hh That Are Localized to Different Cytoplasmic Organelles Eugeni A. Vaisberg, Paula M. Grissom, and J. Richard Mclntosh Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado 80309-0347 Abstract. We describe two dynein heavy chain (DHC)- nantly to the Golgi apparatus. Moreover, the Golgi dis- like polypeptides (DHCs 2 and 3) that are distinct from perses upon microinjection of antibodies to DHC2, sug- the heavy chain of conventional cytoplasmic dynein