阿司匹林和利伐沙班预防全膝关节置换术后下肢深静脉血栓的研究.pdf

IllllllllllllllllI lIIIIIllllllllllllllllllllllkl andRivaroxabantoPreventVenous Administering Aspirin Deep ThrombosisafterTotalKnee Arthroplasty Abstract Objective This aimedto the and of andrivaroxabanfor study compareefficacysafety aspirin post totalknee vein arthroplasty(TKA)deepthrombosis(DVT)prophylaxis． Methods From2011 to 1 203，324 withosteoarthritiswhounderwent July July patients primary unilateralTKAintheAffiliatedof Articularwere HospitalQingdaoUniversitySurgery dividedintothree hoursafterthe randomly groups．Twelve surgery,Rivaroxaban Group Was oral thedoseof10 givenRivaroxaban(Xarelto)at was subcutaneousLMWH thedose Heparin(LMWH)Groupgiven sodium(Clexane)at of andthe Was oral 4，000 AxaIU(0．4m1)／d AspirinGroupgiven thedoseof100 thethree 1 mg／d．All were for4 of groupsgiven days．Comparisons incidence of blood rateandthe DVT,dominant／hidden loss，wound complication incidencesoflowerlimb subcutaneousand weremadeinthethree ecc