最新抗凝策略.ppt

* 低分子肝素（法安明）和普通肝素在滤器使用寿命及出血风险方面均无显著差别 * * * So in CRRT we use a differentt kind of anticoagulation. No heparin and anticoagulating the entire body. Here only the blood circuit is anticoagulated and tri sodium citrate is used to bind calcium. Without calcium blood cannot clot. The citrate binds the calcium. Some calcium is removed in the dialysis process. The citrate gets converted to bicarbonate and the calcium it has been binding is released. The patient has to be given calcium because of the calcium removed in the dialysis process. * 此研究中无抗凝组滤器寿命长于肝素组（但要注意无抗凝组本身就是出血风险较大，入选时血小板水平及INR水平