抗心绞痛药.创新.pptVIP

* Chapter 28 抗心绞痛药 Drugs Used in the Treatment of Angina Pectoris Instructional Objectives 列举抗心绞痛药物分类及代表药。 简述硝酸甘油抗心绞痛作用及机理。 分析硝酸酯类与?－R 阻断药合用治 疗心绞痛是否合理。 §1 Introduction The primary symptom of ischemic heart disease is angina pectoris, which caused by transient (短暂)episodes (发作) of myocardial ischemia. These episodes of ischemia are due to an imbalance in the myocardial oxygen supply-demand relationship. Classification Stable angina pectoris ( 稳定型心绞痛 ) 冠脉粥样硬化，激动或劳累时发作 Unstable angina pectoris (不稳定型心绞痛) 冠脉粥样硬化，血栓，可发展为心梗 或猝死，也可恢复为稳定型心绞痛。 Variant angina pectori