人参与藜芦配伍化学成分变化的HPLC_ESI_MS与ESI_MS研究.pdfVIP

2007 65 Vol. 65, 2007 9 , 829833 ACTA CHIMICA SINICA No. 9, 829833 · · HPLC-ESI-MS ESI-MS a,b a c a *,a (a 130022) (b 100049) c ( 130117) (ESI-MS)(HPLC-ESI-MS), . , , Rf Rb2 ; , . , , . . , . ; ; ; ; ; ; Studies on the Content Variation of Chemical Constituents During the Combination of Ginseng with Veratrum nigrum by ESI-MS and HPLC-ESI-MS ZHANG, Xua,b SONG, Feng-Ruia WANG, Li-Shuc LIU, Zhi-Qianga LIU, Shu-Ying*,a a ( Changchun Center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022) (b Graduate School of the Chinese Academy of Sciences, Beijing 100049) c ( Changchun University of Traditional Chinese Medicine, Changchun 130117) Abstract To study the content variation of ginsenosides and alkaloids during combination of ginseng with veratrum nigrum, the ginsenosides and alkaloids in the decoction of ginseng with veratrum nigrum were analyzed and compared by high performance liquid chromatography-electrospray ionization-mass spec- trometry (HPLC-ESI-MS) and electrospray ionization-mass spectrometry (ESI-MS). In the compatible de- coct