controlled clinical comparison of bactec plus anaerobicstrongfstrong to.pdfVIP

JOURNAL OF CLINICAL MICROBIOLOGY, Mar. 2001, p. 983–989 Vol. 39, No. 3 0095-1137/01/$04.00 0 DOI: 10.1128/JCM.39.3.983–989.2001 Copyright © 2001, American Society for Microbiology. All Rights Reserved. Controlled Clinical Comparison of BACTEC Plus Anaerobic/F to Standard Anaerobic/F as the Anaerobic Companion Bottle to Plus Aerobic/F Medium for Culturing Blood from Adults MICHAEL L. WILSON,1,2* STANLEY MIRRETT,3 FRANCES T. MEREDITH,3,4,5 MELVIN P. WEINSTEIN,6,7,8 VINCENZO SCOTTO,8 AND L. BARTH RELLER3,4,5 1 Department of Pathology and Laboratory Services, Denver Health Medical Center, Denver, Colorado 80204 ; Department of Pathology, University of Colorado School of Medicine, Denver, Colorado 802622; Clinical Microbiology Laboratory, Robert Wood Johnson University Hospital,6 and Departments of Pathology7 and Medicine,8 Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901; and Clinical Microbiology Laboratory,3 and Departments of Pathology4 and Medicine,5 Duke University Medical Center, Durham, North Carolina 27710 Received 26 July 2000/Returned for modification 7 November 2000/Accepted 29 December 2000 To determine the optimal anaerobic companion bottle to pair with BACTEC Plus Aerobic/F medium for recovery of pathogenic microorganisms from adult patients with bacteremia and fungemia, we compared Plus Anaerobic/F bottles with Standard Anaerobic/F bottles, each of which was filled with 4 to 6 ml of blood. The two bottles were paired with a Plus Aerobic/F bottle filled with 8 to 12 ml of blood. A total of 1