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INT’L. J. PSYCHIATRY IN MEDICINE, Vol. 36(1) 13-34, 2006
PSYCHOSOCIAL INTERVENTIONS FOR DEPRESSION,
ANXIETY, AND QUALITY OF LIFE IN CANCER
SURVIVORS: META-ANALYSES*
ROBYN L. OSBORN, MS
ANGELIQUE C. DEMONCADA, MS
Uniformed Services University of the Health Sciences, Bethesda, Maryland
MICHAEL FEUERSTEIN, PH.D., MPH
Uniformed Services University of the Health Sciences, Bethesda, Maryland
and Georgetown University Medical Center, Washington, D.C.
ABSTRACT
Objective: The purpose of this meta-analysis was to investigate the effects of
cognitive behavioral therapy (CBT) and patient education (PE) on commonly
reported problems (depression, anxiety, pain, physical functioning, and
quality of life (QOL)) in adult cancer survivors. Methods: Meta analyses of
randomized controlled trials of CBT and PE were conducted. MEDLINE,
PSYCHINFO and the Cochrane Database were searched from 1993-2004.
The effects of individual versus group interventions and short (8 months)
versus long (8 months) term follow up are also reported. Results: Fifteen
studies met quality criteria. The sample size was 1,492 adult cancer survivors
with an age range of 18-84. 790 were randomly assigned to intervention
groups and 702 to control groups. CBT varied in duration from 4 weekly
one-hour sessions to 55 weekly two-hour sessions. PE ranged from a single
20-minute session to 6 weekly one-hour sessions. Follow up ranged from
1 week to 14 months. CBT was effective for depression (ES = 1.2; 95%
CI = 0.22-2.19), anxiety (ES = 1.99; 95% CI = 0.69-3.31), and QOL
*The opinions or assertions contained herein are the private ones of the authors and are not to be
construed as official or reflecting the views of the U.S. Department of Defense or Uniformed
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