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PLoS MEDICINE
Projections of Global Mortality and Burden
of Disease from 2002 to 2030
*
Colin D. Mathers , Dejan Loncar
Evidence and Information for Policy Cluster, World Health Organization, Geneva, Switzerland
Funding: Financial support for this A B S T R A C T
project was provided by the World
Health Organization (WHO)
Department of Chronic Diseases and
Health Promotion and the WHO Background
Commission on Intellectual Property
Rights, Innovation and Public Health. Global and regional projections of mortality and burden of disease by cause for the years
The funders had no role in study 2000, 2010, and 2030 were published by Murray and Lopez in 1996 as part of the Global Burden
design, data collection and analysis,
decision to publish, or preparation of Disease project. These projections, which are based on 1990 data, continue to be widely
of the manuscript. quoted, although they are substantially outdated; in particular, they substantially under
estimated the spread of HIV/AIDS. To address the widespread demand for information on likely
Competing Interests: The authors
have declared that no competing future trends in global health, and thereby to support international health policy and priority
interests exist. setting, we have prepared new projections of mortality and burden of disease to 2030 starting
Academic Editor: Jon Samet, Johns from World Health Organization estimates of mortality and burden of disease for 2002. This
Hopkins School of Public Health, paper describes the methods, assumptions, input data, and results.
United States of America
Citation: Mat
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