冠心病心力衰竭医辨证分型与corin的相关性研究.pdfVIP

The correlation study of TCM syndrome differentiation of coronary heart disease with heart failure and Corin Speciality：Cardiovascular disease, Internal Medicine of TCM Author ：Zhou Liang Tutor：Wu Yi Nan Abstract Objective：Through testing the Corin and BNP of coronary heart disease with heart failure(CHD with HF),we explore the correlation among the level of Corin and BNP, TCM syndrome of CHD with HF and the severity of heart failure,then provide the clinical basis for the study of integration of Traditional Medicine and Western Medicine. Method ：93 CHD with HF patients were defined in clinic. Collecting the patients general information,including symptom,sign,tongue,pulse and other clinical informations,then all the patients were divided into two clinical types of TCM syndrome: 54 cases of qi-deficiency; 39 cases of yang-deficiency. According to the cardiac function standard of New York Heart Association,We devided patients into three groups: 32 patients were grade Ⅱ,30 patients were grade Ⅲ ,31 patients were grade Ⅳ. 30 healthy voluteers were enrolled as normal control group. The level of Corin was detected by enzyme-linked immunosorbent assay(ELISA).Application of whole blood rapid micro column chromatography was used to test the level of plasma BNP. We analyze these data with the statistics software SPSSl6.0 Results ：1.Through analysing the data between heart failure group and normal control group,we discover that the level of Corin in heart failure group is significantly lower than that in the normal control group(P0.01),but BNP is contrary to Corin (P0.01);2. The severer heart failure(NYHAIIIIIIV ）the lo