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加味交泰丸颗粒疗帕金森病睡眠障碍的临床观察
目 录
中文摘要 ···················································3
英文摘要 ···················································5
引 言 ····················································7
正 文 ····················································8
1. 临床资料 ···············································8
1.1一般资料 ·················································8
1.2诊断标准 ·················································9
1.3 病例纳入标准 ···········································11
1.4 病例排除标准 ···········································11
1.5 病例终止及脱落标准 ····································11
1.6治疗方法 ···············································12
1.7观察指标 ···············································12
1.8疗效评定标准 ·············································12
1.9统计分析 ················································12
2.治疗结果 ···············································13
3.讨 论 ················································15
4.存在的问题和展望 ······································24
结 论 ··················································27
参考文献 ··················································28
附 录 ··········································32
综 述 ··················································42
致 谢 ··················································52
攻读学位期间发表的学术论文目录 ·······················53
作者声明 ··················································54
1
个人简历 ··················································55
2
中 文 摘 要
目 的：评价加味交泰丸颗粒治疗帕金森病（PD ）睡眠障碍患者的临
床疗效。
方 法：采用随机分组的方法，将符合纳入标准的100 例帕金森病睡
眠障碍患者随机分为对照组（50 例）和治疗组（50 例）。对照组口服艾
司唑仑片；治疗组口服加味交泰丸颗粒。两组分别行国际统一睡眠效率
值、帕金森病睡眠量表(Parkinson Disease Sleep Scale ，PDSS) 、匹兹堡睡
眠质量指数 (Pittsburgh sleep quality index ，PQSI) 、爱泼沃斯思睡量表
(Epworth sleepiness scale,ESS)和治疗药物副作用量表( TESS ) 的评分，其
中国际统一睡眠效率值和T
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