清胰化积汤治疗热型慢性胰腺炎的临床研究.pdfVIP

Clinical Study of Treating Chronic Pancreatitis of Damp-heat Syndrome with Qingyihuajitang Specialty：Gastroenterology.Internal Medicine of TCM. Author ：Sun Yangxin Tutor：Professor Lu Guangchao Abstract Objective:To observe the effect of Qingyihuajitang(QYHJT) on Prolapse of Chronic Pancreatitis (CP) and explore the mechanism of it. Methods: 60 patients with CP were divided into two groups at random:the treatment group and the control group. The treatment group was given QYHJT, and the control group was given Qingyilidankeli(QYLDKL).4 weeks were set as a course of treatment.The clinical effects of each group were observed during the course and the follow-up survey of 6 months. Results: The effective of syndrome of TCM, observing of the treatment group are better than that of the control group (P ＜0.01 or P ＜0.05). QYHJT can improve more significantly the symptoms such as abdominal pain, abdominal distention and anorexia fatigue than Qingyilidankeli (P ＜0.01 or P ＜0.05). Conclusions: QYHJT appears to have the significant effect in the treatment of CP. The mechanism of this therapy may be relation to Improve pancreatic microcirculation, Increase in gastrointestinal motility, Anti-inflammatory and Excretion of bile. Keywords Qingyihuajitang(QYHJT) ；Chronic Pancreatitis (CP) ；Damp-heat Syndrome；Clinical study 目 录 引 言 1 临床研究 2 一、临床资料 2 （一）西医诊断标准 2 （二）中医辨证标准 3 （三）病例选择标准 4 （四）病例一般资料 5 二、治疗方法 7 三、观察指标 7 四、评定标准 7 （一）主要症状疗效评定标准 7 （二）中医证候疗效评定标准 8 （三）影像学疗效判定标准 8 五、统计学处理方法 8 六、治疗结果 8 （一）治疗后症状的变化 8 （二）中医证候疗效对比 10 （三）治疗前后症状积分对比 10 （四）治疗前后CT 的变化 11 （五）随访6 个月复发率对比