溃疡性结肠炎伴郁、焦虑的相关因素及中医证候相关性研究.pdfVIP

The study of Ulcerative colitis with depression， anxiety-related factors and the relevance of Traditional Chinese Medicine symptom Speciality： clinical digest department of internal medicine of TCM Author ： Zhang Xin Tutor： Professor Cao Zhiqun Abstract Objective：This study aims at exploring the interrelation between ulcerative colitis and depression and anxiety, and finding out the regularity among common syndromes of ulcerative colitis in TCM. Methods: Using the method of epidemiological survey, basic data and clinical informations of patients with ulcerative colitis were collected, additionally, the patients were asked to assess their severity of depression and anxiety and also fill in questionnaire; and finally all the above data and information were processed and analyzed to find out epidemiological data, potential pathogenic factors and interrelation between syndrome and depression and/or anxiety. Result: 1. The study has shown the incidence of ulcerative colitis is closely interralated with depression and anxiety.2 .With the methods of χ2 test and Logistic regression analysis, the study suggested that some factors such as female , introverted personality and stress can be considered as potential factors leading to ulcerative colitis , the patients at ages between 40-49 in particular. 3. The study showed significant differences in statistics between the patients accompanied by depression and anxiety, and their common syndromes .4.The patients accompanied with depression were often manifested as the syndrome of ‘stagnation of the liver with deficiency of the spleen’, or ‘deficiency of the spleen and stomach; whilst the patients accompanied by anxiety were mostly marked by the syndrome of ‘internal accumulation of dampness and heat’. Conclusion: 1. Pathogenically, ulcerative co