盆腔炎颗粒治疗性盆腔炎的疗效观察及对模型大鼠细胞凋亡影响的研究.pdfVIP

The Clinical Study of PenQiangYan Granule on Treating Chronic Pelvic Inflammatory Disease and The Effect on Inflammatory Related Cell Apoptosis of the Experimental Model Rats Speciality: Gynecology of TCM Author:Xu Qindu Tutor: Prof. Liu Ruifen Abstract Objective: Through the observation pelvic inflammatory disease pellet treatment blood stasis concurrently kidney empty chronic pelvic inflammatory diseases clinical curative effect and the change which perishes weakly to the chronic pelvic inflammatory disease model big mouse cell, discusses the pelvic inflammatory disease pellet treatment chronic pelvic inflammatory disease (CPID) the cell perishes weakly the mechanism, provides the basis for the clinical practice. Method: 60 cases of chronic pelvic inflammatory disease were divided into two groups randomly: Pen Qiangyan Granule treatment group and Pen Yanjing Granule control group, each group of 30 examples. Female Wistar rats were used and the CPID model was established with mixed bacteria injection combined with mechanic injury. Sixty rats were randomly divided into seven groups. After the histomorphological changes of the rats uteri were observed, Immunity set the expression that turn a S-P law to examine each big rat womb organization Caspase-3;Converse to record-the polymerization Mao chain reaction the law(RT-PCR) examine the big rat womb organization Fas/FasLmRNA and the expression of the p 53 mRNAs. Result: The clinical observation result suggests that more showing of the treatment set and matched control comprehensive clinical curative effect rate, always efficient relatively has polar show Zhao discrepancy(P0.01), treatment set curative effect better than matched control;Two sets of Chinese medicine certificates wait more showing of the