经皮穴位电刺激预对卵巢低反应患者妊娠结局影响的临床研究.pdfVIP

Study of the effect of transcutanclus electrical acupoint stimulation intervene in the patients with ovarian poor respond Speciality: Integrated Chinese and Western Medicine Gynaecology Auther ：CHEN Chen Tutor：Professor SUN Wei Abstract Objective ：To investigate the effects and mechanisms of transcutanclus electrical acupoint stimulation (TEAS) changes in serum sex hormone and effect of pregnancy outcome of the patients with ovarian poor respond. Methods: 80 cases women diagnosed of ovarian poor respond or were randomly divided into two groups, 40cases in the observation group and 40 cases in the controlled group. Women in Observation group were offered TEAS for 3 month before controlled ovarian hyperstimulation (COH), compared with the controlled group .Oberved changes in serum sex hormone, number of antral follicle and thickness of endometrium was evaluated before and after intervention. The patients undergoing in-vitro-fertilization and embryo transfer (IVF-ET) adopt short protocol.Observed the doses and days of gonadotrophin （Gn), thickness of endometrium on the hCG injecting day.Compared, number of matured oocytes outcome ， the rate of fertilization， high grade oocyte and embryo, cryopreservation of embryo,cycle canceling rate were analyzed. Results: 1. 3 cases in observation group got spontaneous pregnancy, with obvious decrease of basal FSH of the level after 3 month’s intervention （P ﹤0.05 ）. Number of antral follicle has been increased significant significantly （P ﹤0.05 ）.2 .level of E2 and thickness of endometrium on the hCG injecting day has been significantly improved （P ﹤0.05 ）.3.Compared with the controlled group ,the number of retrieved oocy