复健片调控ne网络干预肝肾阴虚证以“异病同治”的理论与临床研究.pdf

提 要 目的：探讨滋补肝肾中药复健片调控神经一内分泌一免疫(NEI)网络干预肝肾阴 虚证以“异病同治’’的微观机制。方法：基于“异病同治的中医理论，以老年性痴 呆及中风后遗症的肝肾阴虚患者为研究对象，观察复健片对肝肾阴虚证的干预作用， 初步探索滋补肝肾中药“异病同治的微观机制。临床研究分为三部分：(一)观察 复健片干预肝肾阴虚证，对老年性痴呆的治疗作用；(--)观察复健片干预肝肾阴虚 证，对中风后遗症的治疗作用；(三)探讨复健片调控NEI网络干预肝肾阴虚证以“异 病同治的微观机制。结果：老年性痴呆和中风后遗症肝肾阴虚证患者NEI网络存在 节内分泌系统的功能，可通过调控紊乱的NEI网络干预肝肾阴虚证候，对老年性痴呆 和中风后遗症均有较好的疗效。结论：NEI网络是肝肾阴虚证的生物学基础之一。滋 补肝肾中药可通过调控!NEI网络，干预肝肾阴虚证候，进而达到“异病同治”的目的。 关键词异病同治；肝肾阴虚证；神经一内分泌一免疫网络；滋补肝肾；复健片 Oll Tablet Different and Studies TheoreticalClinical Fujian Treating Intervene ofNEIto Diseases theHomeostasis byRegulating ofLiverand Yin Deficiency Syndrome Kidney ofnervous diseases andclinicalonthetreatment system study Speciality：Experimental Medicine withTraditionalChinese Xinlu Tutor：Prof．Wang Author：Han Ping Abstract mechanismof is themicrocosmic Tablet(which Objective：Toinvestigate Fujian differentdiseases to“nourishliverand by formulated kidney’’)treating specifically thehomeostasisofNEItointervene ofliverand deficiency． regulating syndrome kidneyyin withthesame Methods：Basedonthe differentdiseases therapy’’in