清氮灌肠方治疗性肾功能衰竭的临床及实验研究.pdfVIP

th e C lin icalan d E xP erim en talR esearch of Q in g D an G u an C h an g F a n g o n C h ro n ic R en a l F a ilu re S P ecia lty :T h e stu dy of K idn ey D iseases.In ternalM ed iein e of T C M A u th o r :L i J in g T u to r :P ro fesso r G u o Z h ao an A b str a e t O bjeetive : TO observe X iezhuo Jiedu and We nyang H uoxue enem a treatm ent on Patienrs w ith chrollic renal failure (C 盯 )，assess the effe ets of th is treatm ent on renal fun etio n an d P ath o lo g y o f s/6 n eP hreeto m y rats w ith C R F an d ex P lo re th e m eeh axlism . M eth o d : 1. C lin ieal re seaeh : 10 0 P atien ts 俪 rh C R f w ere ran d o m 了y d iv id ed in to exP erim ental and eontrol grouP s. T h e exPerim ental grouP w ere treated w ith Q ing D an G u an C h an g F an g b e sid e s eo n v en tio n a l tre atm en t，o n ee a d ay ，w h ile th e eo n tro l g ro u P treate d w ith a i x i te ，3 0 P ills o n ee . A fter 3 m o n th s’treatm en t，w e o b serv e d th e eh an g e s in sym Ptom seore of renalfunetion ，hem oglob in (H b)，Parathyroid horm one (PT’H ) and T C M H o u o f sP leen d e行e ien ey an d tu rb id sta sis b lo ck ，eo m P ar in g th e d iffe ren t e lin iea j e价 ets o f th e tw o lreatm en ts. 2 . A n im a l ex P erim en ts : 10 o f 6 0 m a le W israr rats w ere ran d o m ly d iv id e d in to 11o rnla l g ro u P an d th e re sz w ere e stab lislled a s C 盯 m o d e ls b y s /6 n eP h re eto m y . A w e ek after oP eratio n ，m o d e ls th at w ere estab lish ed a s ex P eeted te stin g b y b ]o o d tak en fro m th e ta i] v e in w ere ran d om ly d iv id ed in to 4 gro u P s :m o d e l g ro u P ，a i x i te grouP (eon trol grouP