VALUE研究和MATCH研究PPT课件.pptVIP

VALUE and MATCH: An era of comparative clinical trials Eric J Topol MD Provost and Chief Academic Officer Chairman, Department of Cardiovascular Medicine Cleveland Clinic Foundation Cleveland, OH Robert M Califf MD Professor of Medicine Associate Vice Chancellor for Clinical Research Director, Duke Clinical Research Institute Duke University Medical Center Durham, NC Topics VALUE: Goal Trial designed to compare two treatment strategies: amlodipine (Norvasc?, Pfizer) and valsartan (Diovan?, Novartis). (Lancet 2004 Jun 19; 363:2022-31.) STUDY AIM If similar blood-pressur