肾动脉狭窄支架术现状详解.ppt

Renal stenting in renal artery stenosis----contented and uncontented 肾 动 脉狭窄支架术  ARAS 90% FMD 10% Haemodynamics: 　50%　Renal perfusion pressure reduction 　70%　RPP75-85mmHg, autonomic regulation lose　 Pathology: Glomcrulus：arteriosclerosis, mesenterium proliferation， Nephric tubule：epithelial cells denudation、apoptosis,Focal necrosis， Renal interstitium：Inflammatory cell infiltration、fibrocyte proliferation End stage ：renal atrophy Develop to total occlusion within 5 years 15% Deterioration gradually within 5 years 10-20% Develop to ESRD annually