COMET研究PPT课件.pptVIP

COMET: Carvedilol Or Metoprolol European Trial Purpose To compare the effects of carvedilol (a β1-, β2- and α1-receptor blocker) and short-acting metoprolol tartrate (a β1-receptor blocker) on clinical outcome in patients with chronic heart failure Reference Poole-Wilson PA, Swedberg K, Cleland JGF et al. for the COMET Investigators. Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial. Lancet 2003;362:7–13. COMET: Carvedilol Or Metoprolol European Trial-