低电压电泳芯片设计理论ansys模拟教程分析.docVIP

摘 要 电泳分离技术以其高效、快速、微量、易自动化等优点在生命科学医学药物、环境保护等领域得到了极其广泛的应用。随着芯片上的实验室思想的提出和微型全分析系统的发展，使得在芯片上进行电泳分离的技术成为了当今国内外的重要研究热点。 本文首先简要介绍了电泳芯片的研究和发展概况，然后讨论了电泳芯片中常见的毛细管电泳芯片的工作原理，详细介绍了具有代表性的毛细管低电压电泳芯片，分析了其内部的结构及其电场分布，然后利用ANSYS12.0软件对分析进行模拟仿真，并粗略的分析其结果。本文着重介绍了毛细管低电压电泳芯片的流体通过900弯道情况，讨论了不同弯道形状对流体通过弯道时的影响，利用ANSYS软件模拟出相关的现象，更直观的反应结果，充分验证了窄弯道对流体等速通过弯道有着很明显的影响[1]。 本论文以期在了解毛细管电泳的相关理论的基础上，建立电泳芯片的低电压运动梯度场的分离和控制模型，对低电压电泳芯片的制作和研发进行前期探索，为研制一种微型化，集成化的低电压电泳芯片奠定一定的理论和技术基础。 关键词：电泳芯片，分离芯片，低电压电泳芯片，牛顿流体，模拟仿真  Abstract With advantages of high efficiency, real time, low volume and automation, capillary electrophoresis separation techniques have been widely used in industrial analysis, biomedicine, Molecule biology etc. With the pretence of lab on the chip and the development of micro total analysis system, electrophoresis chip, capillary electrophoresis technology on a chip, became the research hot of micro electromechanical system. In this thesis, the current research and development of the Electrophoresis Chip was first introduced, Then the work principle of the low voltage micro electrophoresis chip, which is important in the biochip was discussed. The simulation of the electrical field distribution was conducted using ANSYS 12.0. And analysis on the results was given. This thesis is focused on the case when the fluids in capillary electrophoresis chips go through the curved conduit. Using the ANSYS software, the simulation of related fluidic phenomena was conducted, and the results verified that the narrow curved conduit was a clear impact when fluid goes through the curved conduit with a uniform velocity. The paper based on the knowledge of capillary electrophoresis technology, the separation and control models of low voltage electrophoresis system using moving grade electrical field have been presented. At the same time, the developments of electrophoresis chip and control circuit have been studied, which will lay theory and technique foundation for the further study on the low voltage electropho