生工工程-王丽媛-8000L-乳酸工段工艺设计.docVIP

毕业设计（论文）手册 课题名称： 8000吨/年L-乳酸工段工艺设计 学 院： 生物工程学院 班 级： 生物工程1020班 学 号： 0909030108 姓 名： 王丽媛 指导教师： 姚秀清 8000吨/年L-乳酸发酵工段工艺设计 王丽媛 （辽宁石油化工大学，石油化工学院，生物工程1037） 摘 要 L-乳酸是一种重要的食用有机酸，需求量仅次于柠檬酸，可用于食品工业、医药工业和制造生物可降解聚合物等多个领域。L-乳酸除了具备普通乳酸的性质外，另外还具有独特的生化价值，被广泛的应用于食品、医药、化工等行业。 经过查阅大量的文献资料，首先确定了本设计中的发酵原料、发酵菌种、发酵方法，在此基础上确定了L-乳酸发酵工段工艺流程。本设计以薯干为原料，以米根霉为发酵菌种，采用乳酸传统发酵方法。根据年生产量对发酵过程进行了物料、热量衡算。经过衡算，给出了8000吨/年L-乳酸发酵工段所需要消耗的物料量以及消耗的蒸汽量、冷却水量。依据衡算结果，在选定高径比（H/D=2）条件下，设计了发酵罐、种子罐的主要尺寸和个数，并给出了发酵罐换热器的传热面积，搅拌器的轴功率、通气量等。另外又设计了配料罐体积。最后可根据上述计算得出的数据绘制了工艺流程图、发酵罐三视图及发酵车间发布图。 关键词： L-乳酸，发酵，工艺设计 The fermentation process design of L-lactic acid with an annual output of 8000 tons Wang liyuan (Class 1002, School of Bio-engineering, Liaoning Shihua University, Fushun, 113001, Liaoning) Abstract L- lactic acid was an important edible organic acid and the demand was only smaller than the citric acid, which could be used in various fields of food industry, pharmaceutical industry and be manufactured biodegradable polymers. L- lactic acid not only had the nature with ordinary lactic acid, also had unique biochemical value. It was widely used in food, medicine, chemical industry etc. Through access to information, raw materials, strain production and method of fermentation in this design were first identified. Based on this, process flow of L- lactic acid was given. In this design, Sweet potato was selected as raw materials and Rhizopus oryzae was strain. Materials, energy and major equipment structure size were calculated. At the same time, the required amount of material consumption,steam consumption and consumption of cooling water were given for 8000 tons / year an annual output of 8000 tons of L- lactic acid. According to the calculation results, with the selected ratio of height to diameter (H/D=2), the main dimension and number of fermentation tanks and seed tanks were calculated. The heat transfer area of fermentat