体内药物中的现代方法与技术教案解析.ppt

特 点 毛细管电泳的基本原理 电泳分离的基础 毛细管电泳 毛细管电泳装置 毛细管区带电泳 毛细管凝胶电泳 毛细管等速电泳 Process Needed to Generate a Mass Spectrum Generate desolvated ions (Sources) Transfer ions into mass spectrometer vacuum (Interface Region) Mass analyze ions (Quadrupoles in vacuum condition) Detect ions (Detector in vacuum condition) Process the Data (Software) Q1 full scan Q3 full scan Selected ion monitoring (SIM) Product ion scan Precursor ion scan Constant neutral loss scan Multiple reaction monitoring (MRM) Q1 MS Scans Q3 MS Scans Many precursor to product ion pairs can be monitored (A-B, A’-B’, etc.) MRM is the best w