儿童大脑神经母细胞瘤MRI诊断定稿.docVIP

儿童大脑神经母细胞瘤MRI诊断 张超群 彭望书 田志强 周欧平 刘益平 阳长华 410205 湖南长沙 中国航天湖南航天医院 摘要 目的：探讨儿童MRI的影像特点。方法：对经手术及病理证实的例儿童幕上患者的MRI资料进行回顾性分析。本组例患儿均行颅脑MRI常规平扫增强扫描。结果：例肿瘤均位于幕上，包括。病灶呈类圆形或分叶状，边界清楚。T1WI呈稍低或低信号，T2WI呈稍高或高信号。，。增强扫描例明显强化。结论：儿童PNETs MRI表现具有一定的特点，根据肿瘤部位、边界、信号、水肿、增强特点有助于该病的诊断和鉴别诊断。MRI diagnosis of Brain neuroblastoma in Children ZHANG chao-qun,PENG wang-shu,Tian zhiqiang,ZHOU ou-ping,YANG chang-hua,YU jian-hua 410205 HuNan Hang tian Hospital of China Aerospace Abstract Objective: Children of MRI brain images of neuroblastoma Features. Methods: After surgery and 3 cases of children with pathologically confirmed supratentorial brain MRI in patients with neuroblastoma were retrospectively analyzed. The group 3 patients underwent conventional brain plain and enhanced MRI scans. Results: 3 cases were loca- ted in supratentorial tumors, including 1 case of frontal lobe, parietal lobe in 2 cases. Lesions were round or lobulated, clear boundary. T1WI showed a slightly uneven or low signal, T2WI showed a slightly higher or high signal. Seeing a case of cystic degeneration and hemorrhage, see mild peritumoral edema. Enhanced scan were seen in 3 cases significantly enhanced. Conclusion: Children PNETs MRI has certain performance characteristics, according to tumor location, boundary, signal, edema, enhanced features contribute to the diagnosis and differential diagnosis. Key words: Brain Neuroblastoma, MRI diagnosis, Tumor, Imaging features 大脑神经母细胞瘤归属于幕上原始神经外胚层肿瘤（PNET[1]，它是一种的高度恶性的神经系统肿瘤2008年月～20年月经MRI检查后我院或外院手术病理证实的幕上，探讨其MRI表现特点，以提高诊断准确率。1.2??临床表现? 头痛、呕吐、颅内高压症状例，其中伴有肢体无力及抽搐例，伴有步态不稳表现1例单纯头痛例。1.3? 检查方法?采用美国公司生产的1.5T型超导磁共振扫描仪，运用SE序列，层厚10mm，层距5mm，例肿块均位于幕上，。本组病例肿块均较大，均位于脑实质内，占位效应明显，最者cm×7.2cm×6.5cm；位置邻近脑膜，但周围脑膜无明显增厚；肿块形态边缘清楚周围可见轻度水肿，T1WI呈稍低或低信号，T2WI呈稍高或高信号其中2例内可见脑脊液样T1、T2信号环状强化，肿块周围脑膜无明显。 图1T1WI横断位、矢状位及T2WI横断位：边缘尚清，肿块周围水肿，占位效应明显，T1WI呈稍低或低信号，T2WI呈稍高或高信号 T1WI增强矢状横断位、冠状，环状强化，肿块周围脑膜无明显?CT扫描⑥见大囊变与斑片状、团块状钙化。病理肿瘤由弥漫密集的原始小圆细胞组成，核浓染，核-浆比例高，核分裂多Vim，CD99，CgA瘤组织内细胞密集丰富，细胞形态较单一，为小圆形、卵圆形或不规则，染色质呈细颗粒状，，并见