Infertilityandassistedreproductivetechnology(不孕症和辅助生殖技术)资料祥解.ppt

Infertility and assisted reproductive technology contents Infertility Definition Causes Examinations and diagnosis Treatent Assisted Reproductive Technologies(ART) Intra-uterine insemination(IUI) In Vitro Fertilization and Embryo Transfer(IVF-ET) Intracytoplasmic sperm injection(ICSI) Gamete intrafallopian transfer(GIFT) Definition of Infertility Infertility is defined one year of unprotected intercouse without pregnancy Primary Infertility:no previos pregnancies have occurred Secondary Infertility:a prior pregnancy has occurred causes Causes Percentage Female factors 40% Male factors 30-40% Both male and female factors 10-20 % Immunologic unexplained factors 10 % Ovulatory Dysfunction 1. Hypothalamic dysfunction; 2. Pituitary Insufficiency; 3. Ovarian factor (peripheral defect); 4. Others: thyroid or adrenal dysfunction; Pelvic Factors 1. Tubal factors: injury, blockage, adhesion 2. Uterine factors: cogenital anatomic abnormalities endometrium disorder, tumor 3. Cervical factors: infection, cogenital abnormalities 4. Extra-genital tract factors: infection, cogenital abnormalities Male Factors 1. Abnormal spermatogenesis congenital; chronic diseases; infectious factors; 2. Obstructive: sperm transport abnormalities; 3. Immunologic factors; 4. Endocrine disorders; 5. Sexual dysfunction; Examinations Special Laboratory Examinations: semen analysis(精液分析); hormone measurement; sperm penetration assay (SPA)精子穿透试验; postcoital examinition of c