第章DNA的复制分析.pptVIP

ligase c) Replication of linear Adnovirus-2 DNA 35937 bp pTP C G IR 103-162 IR ; including 50 bp replication origin rich AT 1th C/G high conversation pTP ; pre-Terminal protein 80 kd → TP 55 kd SSB ; S.S. DNA binding protein 72 kd Ad2 DNA polymerase ; 140 kd 复制起始复合体 引发复制 （不需引物） 避免5’-end shorten pTp-Ser-dCMP C G ● 过程 SSB + ATP DNA 末端解链 TP pTP-Ser + dCTP pTP-Ser-dCMP 3‘ OH IR IR C G G C G C C G pTP-Ser-dCMP