食品添加剂—--亚硝酸盐.docVIP

文献检索报告 学 院：理学院 专业班级：应用物理0801 姓 名：肖庆宇 学 号：20084841011 题 目：食品添加剂亚硝酸盐 作为食品添加剂的亚硝酸盐 检索关键词 中文关键词：食品添加剂、亚硝酸盐 Key World： 2.采用维普，以食品添加剂and亚硝酸盐为检索式，《正确看待亚硝酸盐》、 《正确看待亚硝酸盐》 关键词：食品添加剂；亚硝酸盐；中毒 摘要：硝酸盐和亚硝酸盐是广泛存在于自然环境中的化学物质，特别是在食物中，如粮食、蔬菜、肉类和鱼类都含有一定量的硝酸盐和亚硝酸盐。它是一种允许使用的食品添加剂，只要控制在安全范围内使用不会对人体造成危害。 3.采用EBSCO Host，以Food additives and Nitrite为检索式， spectroscopy to study interactions of iron proteins in cells with nitric oxide》 spectroscopy to study interactions of iron proteins in cells with nitric oxide》 Key World: EPR spectroscopy; Nitric oxide; Food preservation; Parkinson’s disease Abstract ：Nitric oxide and species derived from it have a wide range of biological functions. Some applications of electronparamagnetic resonance (EPR) spectroscopy are reviewed, for observing nitrosyl species in biological systems. Nitrite has long been used as a food preservative owing to its bacteriostatic effect on spoilage bacteria. Nitrosyl complexessuch as sodium nitroprusside, which are added experimentally as NO-generators, themselves produce paramagnetic nitrosyl species, which may be seen by EPR. We have used this to observe the effects of nitroprusside on clostridial cells. After growth in the presence of sublethal concentrations of nitroprusside, the cells show they have been converted into other, presumably less toxic, nitrosyl complexes such as (RS)2Fe(NO)2. Nitric oxide is cytotoxic, partly due to its effects on mitochondria. This is exploited in the destruction of cancer cells by the immune system. The targets include iron–sulfur proteins. It appears that species derived from nitric oxide such as peroxynitrite may be responsible. Addition of peroxynitrite to mitochondria led to depletion of the EPR-detectable iron–sulfur clusters. Paramagnetic complexes are formed in vivo from hemoglobin, in conditions such as experimental endotoxic shock. This has been used to follow the course of production of NO by macrophages. We have examined the effects of suppression of NO synthase