影响中低位直肠癌淋巴结获取数目临床病理因素分析.pdf

摘要 行新辅助治疗病例中，粘液腺癌，印戒细胞癌淋巴结获取数目高于腺癌，差异有统计学意 义 中位数17．00 VS．9．00，p 0．01 。淋巴结转移状态影响淋巴结获取数目，差异有统计 组、病理类型及CEA水平组间阳性淋巴结获取数目差别有统计学意义。 结论 中低位直肠癌淋巴结获取数目存在个体问差异，受多因素影响，其与肿瘤 大小、年龄及手术方式相关；肿瘤大小及年龄影响淋巴结获取数目大于等于12枚。 关键词：直肠癌，淋巴结获取数目，新辅助治疗，影响因素 第1I页 ABSTRACT factors nodesharvestedin Clinicopathological influencinglymph ‘1 l’ 一 midannlow rectalCancer Major：Surgery Name：LiangJinglin Supervisor：Prof．HuangMeijin ABSTRACT objective numberof nodesharvestediscriticalforthe nodal Adequate lymph adequate in withrectalcancer．Andseveralstudies thatthenumber of stagingpatients suggest lymph nodesharvestedinsome wi吐lcolorectal 1 cancerwaslessthan2．Andresentstudies patients also thatthe numberof nodesrecoveredincolorectalcancerresection suggests lymph be a factor．Thiswas todeterminetheclinicaland specimensmay prognostic studydesigned factors thenumberof midandlow in pathologicalinfluencing lymphnodes LNs harvested rectalcancer clinicaldata． by analyzing Methods Between 2007andDecember on whounderwent 2009，data January patients forlowandmidrectalcancerfromthesixthaffiliated ofSunYat-sen surgery hospital werecollected．Atotalof224 were 45 treated University patientscollected，includingpatients 、析tll and factors thenumberofLNs neoadjuvant pathological therapy．Clinical affecting of LNsand12 more harvested，number or harvestedLNswere positive analyzed retrospectively． Results ThemediannumberofLNsharvestedof treated Was patientsneoadjuvanttherapy 1 the treatedwithout Was O．00 interquartilerange8 ，whilepatients neoadjuvant therapy 1 wasa differencebetweenthesetwo 6．00 interquartilerange8 ，there statisticallysignificant associated、 l，ithalowernumberof groupsO 0．001 ．Olderpatients 65yearsold Was recoverednodes to than65 16．00VS．1 comparedpatientsyoungeryears old median4．00，P 1 0．09 ．TstageQ。O．00 size，operative and nodestatus 1 ，tumor procedure，surgeonslymph hada numberofLNs influenceonthe harvested．In significant categoricalregressionanalysis， 第llI页 ABSTRACT thefactorsthat