骨髓细胞学检查英文课件(第一部分).ppt

Testing of bone marrow cytology (1);Ⅰ. The generation, development and normal morphology characteristics of blood cell;1. Generation of blood cells;Stem cell;Mononuclear cells;2. General principles of morphological evolution during the development of blood cells;With the development and maturity of blood cells: (1)Cell volume: from big to small (2)Cytoplasm: 1)volume increased 2)Color turns from deep blue to light blue, even carmoisine 3)Granules in cytoplasm: no granules→azurophil granules→specific granules(neutral, acidophilic and basophilic strippling);(3)nucleus: 1)Size: from big to small From regular to irregular, even with sublobes 2)Chromatin: from fine to rough, tight and dense, color changes from light to deep 3)Nucleole: clear→blurred→disappeared 4)Nuclear membrane: unclear→clear ;;Evolution of blood cells, 1000x;Normal morphologic characteristics of blood cell;;(1)normoblast;(2)basophilic erythroblast;;;(5) Reticulocyte;;2. Granulocyte series;(2)promyelocyte Shape: round or elliptical Diameter: 12-22μm Nucleus: big, round or oval Chromatin: thick granular or net-like, distributing unevenly Nucleole: clear or disappeared Cytoplasm: comparatively much, light blue or blue Sometimes there is olistherozone near the nucleus Granules: non-specific azurophilic granules, distributed unevenly, with different size, shape and quantity;Comparison of 3 kinds of myelocyte;Neutrophilic myelocyte;;Because of the basophilic granules in the cytoplasm, the nucleus is unclear and the structure of the chromatin is vague.;(4)metamyelocyte Shape: round or elliptical Diameter: 10-16μm Nucleus: kidney-like Chromatin: rough and chunk-like, arranged densely Cytoplasm: abundant, salmon pink, with different specific granules(neutral, acidophilic, basophilic);Neutral metamyelocyte;(5)stab granulocyte Shape: round Diameter: 10-15μm Nucleus: long and narrow, girdle-shaped, both ends are blunt and round Chromatin: rough and chunk-like Cytoplasm: specific granules(neutral, acidophilic, b