人类群体遗传学—第七讲资料.ppt

人类群体遗传学基本原理和分析方法 ;序号; 第五讲; 第五讲;基本概念;单核苷酸多态性;genotype;From genotype to haplotype;Reconstruct haplotype from genotype;Reconstruct haplotype at individual level ;软件演示;PHASE input file format;Position and Locus type;Genotype coding;Example of input file format;PHASE input file format;Alterative format;Options affecting run times and accuracy;Running PHASE multiple times;Running several data sets from the same input file;Linkage Disequilibrium (LD);连锁不平衡;;Commonly used LD measurements;Independence test（p-value）;Population recombination rate (4Ner);Human recombination rate;4Ner and LD;LD统计量的性质- |D’