artificialtissues精编.pptVIP

Artificial tissue PPT制作：陈利红，马琪 PPT汇报：陈利红 ，马琪 答疑：刘文艳 资料检索: 刘文艳 1.Grown in the laboratory. 2.used as a tissue replacement. 3.For people with tissue trauma. 3 Tissue engineering can be defined as “an interdisciplinary field(学科领域) that applies the principles of engineering and the life sciences towards the development of biological substitutes that restore, maintain, or improve tissue function” Research method 隐形眼镜 人工耳蜗 静脉主导管 血管支架 起搏器 静脉导管 胆道内支架 血液透析产品 骨科植入体 伤口引流导管 Evolution of Biomaterials Structural Functional Tissue Engineering Constructs Soft Tissue Replacements 软组织的替代品 结构学范畴 组织工程材料 implants using common and borrowed materials. 01 developed through collaborations of physicians and engineers. 02 Some modified and new polymeric devices. 03 First Generation Implants PMMA dental prosthesis（假肢，假体） glass eyes and other body parts wooden teeth bone plates Intraocular Lens（人工晶体） 3 basic materials - PMMA, acrylic, silicone 聚甲基丙烯酸甲酯，晴纶，硅 Vascular Grafts（血管移植） heart valves （心脏瓣膜） pacemakers（心脏起搏器） surfaces for total joint replacements Second generation implants Artificial Hip Joints(髋关节） Third generation implants Substitute Heart Valves Biomaterial(生物材料) is any substance (other than drugs) or combination of substances synthetic or natural in origin, which can be used for any period of time, as a whole or as a part of a system which treats, augments, or replaces any tissue, organ, or function of the body. 1 2 3 Bioresorobable vascular graft （可吸收的血管组织） Biodegradable nerve guidance channel（可生物降解的神经通道） Skin Grafts（皮肤移植) Biomaterials for Tissue Replacements 4 Bone Replacements(骨移植) Cell matrices（矩阵） for 3-D growth and tissue reconstruction Biosensors, Biomimetic(仿生), and smart devices. Controlled Drug Delivery/ Targeted delivery Advanced Biomaterials Technology 16 Eliminate the need for tissue typing. Advantages of artificial tissue Made in large quantities and frozen for storage and shipping. Severely curtailing (减弱) the chance of infection. Not rejecte