短暂性脑缺血发作与颈内动脉内中膜厚度相关性的初步研究(精选).docVIP

短暂性脑缺血发作与颈内动脉内中膜厚度相关性的初步研究 【摘要】目的 探讨短暂性脑缺血发作继发脑梗死与颈内动脉内中膜厚度的关系。方法 回顾性分析短暂性脑缺血发作（TIA）的患者90例。所有患者均行颈部超声检查，并随访一个月，了解其脑梗死发生情况。采用受试者工作特征曲线（ROC）分析颈内动脉内中膜厚度预测TIA继发脑梗死可能。结果 颈内动脉内中膜厚度为（0.96±0.18）mm，随访１月后TIA患者发生脑梗死16例（发生率约17.8%），内中膜增厚组与未增厚组脑梗死发生率不同（(2＝4.514，Ｐ＜0.05）；颈内动脉内中膜厚度预测TIA继发脑梗死价值的ROC曲线下面积为0.73（P＜0.05）。 结论 TIA患者具有较高的颈内动脉粥样硬化发生率，颈内动脉内中膜增厚对预测TIA继发脑梗死的发生有一定价值。 【关键词】：短暂性脑缺血发作; 颈内动脉内中膜厚度；脑梗死 Preliminary study of the correlation of transient ischemic attack and carotid artery thickness Liu Xudong1; Zhang Ziyin 2 ; 1 Department of Neurological; Ziyang Frist People’s Hospital; Ziyang, Sichuan; 641300; China 2 Department of Neurosurgery, Affiliated Hospital of Hainan Medical College, Haikou, Hainan, 570102, China. Corresponding author: ZHANG Ziyin, Email:270883089@ [Abstract] Objective To investigate the correlation between carotid artery intima-media thickness and cerebral infarction secondary to transient ischemic attack . Methods A retrospective analysis of 90 cases in ATI was done seriously . All the cases underwent neck ultrasonography, and followed up for one month in order to understand the incidence of cerebral infarction. We try to find the possibility that using receiver operating characteristic curves(ROC) analysis of carotid artery intima-media thickness to predict the occurrence of cerebral infarction secondary the TIA. Results The mean carotid intima-media thickness of all the caese was (0.96?.18)mm. After followed up for one month, 16 cases had cerebral infarction(17.8%). The incidence rate of cerebral infarction are differences between intima-media thickening group and no thickening group((2＝4.514, Ｐ＜0.05). The area under the curve of ROC which biulded by carotid artery intima-media thickness and cerebral infarction secondary to TIA is 0.73（P＜0.05）. Conclusions TIA patients have higher incidence of carotid atherosclerosis. Carotid artery intima-media thickness has a certain value in predicting cerebral infarction secondary to TIA. [Key words] Transient