1 540nm非剥脱点阵激光治疗亚洲人皮肤瘢痕的临床研究.docVIP

1 540nm非剥脱点阵激光治疗亚洲人皮肤瘢痕的临床研究 　　[摘要]目的：本研究旨在探讨1 540nm波长的非剥脱点阵式铒玻璃激光应用于华人皮肤不同凹陷性瘢痕治疗的疗效和安全性。方法：本研究采用1 540nm波长的非剥脱点阵激光，选取20例轻到中度凹陷性瘢痕的患者，应用Lux 1 540TM灯泵铒玻璃激光器+微透镜阵列治疗仪对瘢痕行多次治疗，通过治疗前后的临床及照相来评价疗效，并随访患者满意度和可能发生的副作用。结果：所有病例均有改善，有6例患者（30.0%）的临床改善结果达到接近完全改善（76%到100%），8例（40.0%）显著改善（51%到75%），1例（5.0%）有很小或没有改善。患者的满意度调查显示，20例患者均认为治疗有效，有17例（85.0%）评分在8～10分，与临床评分基本一致。结论：应用1 540nm波长的非剥脱点阵激光治疗仪进行面部凹陷型瘢痕的治疗是一种有效、安全的技术。 　　[关键词]凹陷型瘢痕；StarluxTM 1540；1540nm波长点阵激光 　　[中图分类号]R616.4 [文献标识码]A [文章编号]1008-6455（2014）14-1170-04 　　The use of 1540 nm fractional photothermolysis for scar treatment in Asian skin 　　QIAN Huan1，ZHENG Min2 　　（1.Department of Plastic surgery，The Second Affiliated Hospital of Zhejiang University School of Medicine，Hangzhou 310052，Zhejiang，China；2.Department of Dermatology，The Second Affiliated Hospital of Zhejiang University School of Medicine） 　　Abstract： Objective This study aim to evaluate the efficiency and safety of 1 540 nm erbium：glass fractional laser in the treatment of atrophic scars in Asian skin. Methods Twenty volunteers with mild to moderate atrophic scars，such as acne scar and surgical scars，were enrolled.Scar lesions were treated with 1 540 nm fractional photothermolysis （StarluxTM 1 540）.A series （typically 2 to 6 treatments） treatment sessions were conducted for each patient at 4 weeks intervals.Assessments included grading on a 4-point scale by two independent physicians using digital photography taken before and after the treatment and patients’ satisfaction with the treatment. Side effects were evaluated as well. Results A mild to moderate clinical improvement was seen for atrophic scars in majority of patients. Relative to baseline， 6 patients had an improvement of greater than 75% in scarring， 8 patients had a 51% to 75% improvement， and 1 patient had less than a 25% response to treatment. 85.0% of patients were overall satisfied with the treatment， which paralleled the physicians assessment. Conclusion The advanced technology provides an ef