早期输注大剂量氨基酸对早产儿营养状态的影响.docVIP

早期输注大剂量氨基酸对早产儿营养状态的影响 　　[摘要] 目的 分析早期输注大剂量氨基酸对早产儿营养状态的影响。 方法 将本院收治的60例接受肠道外营养治疗的早产儿分为观察组（30例）和对照组（30例）。观察组行大剂量氨基酸静脉输注，对照组行小剂量氨基酸静脉输注，同时两组均在接受氨基酸肠外营养方案的基础上辅助行“全合一”静脉营养方案。于早产儿出生第14天，计算统计两组的相关生长发育指标和营养及代谢指标。 结果 出生后第14天，观察组早产儿体质量下降幅度小于对照组（P0.05）。 结论 早期输注大剂量氨基酸有助于改善早产儿的营养状况，促进早产儿生长，且对机体代谢影响小，安全性好。 　　[关键词] 早产儿；肠外营养；大剂量氨基酸 　　[中图分类号] R722.6 [文献标识码] A [文章编号] 1674-4721（2014）09（b）-0082-03 　　The influence of large dose of amino acid early infusion on nutritional status in premature infants 　　YANG Qing-ping 　　Department of Neonatology，the Third Hospital of Jingdezhen City in Jiangxi Province，Jingdezhen 333000，China 　　[Abstract] Objective To analyze the influence of large dose of amino acid early infusion on nutritional status in premature infants. Methods 60 premature infants admitted to our hospital for treatment of parenteral nutrition were divided into observation group （30 cases） and control group （30 cases）.Large dose of amino acid infusion was given to the observation group，small dose of amino acid infusion was taken to the control group，at the same time，two groups of preterm infants were given with all in one intravenous nutrition scheme based on an amino acid parenteral nutrition solutions.In section 14 days，the growth and development indicators and indicators of nutrition and metabolism of two groups were calculationed and statisticsed. Results 14 days after birth，the premature infants body weight decreasing of observation group was less than that of the control group （P0.05）. Conclusion Large dose of amino acids early infusion can improve the nutritional status of premature infants，can promote the growth of premature infants，and the influence to metabolism is small，has good safety. 　　[Key words] Premature infants；Parenteral nutrition；Large dose of amino acids 　　近年来，随着辅助生殖技术发展进程的不断推进以及产科监护治疗手段的日益发展，早产低体重儿的出生率逐年上升。相关临床研究报道指出极低出生体重儿生后第1周的营养供给甚至与远期认知发育紧密相关[1]，因此，制订早产儿能量及营养支持的最佳方案，使其生理性体重下降结束后能保持与同胎龄宫内发育儿一致的生长速度成为当前临床新生儿科医生亟待解决的问题之一[2]。长期以来，肠外静脉营养支持是救治极低和超低出生体重儿