右美托咪定预防行椎内麻醉的剖宫产患者寒战的临床分析.docVIP

右美托咪定预防行椎管内麻醉的剖宫产患者寒战的临床分析 【摘要】 目的：探讨右美托咪定预防剖宫产患者椎管内麻醉期间寒战反应的临床疗效。方法：将我院2011年11月至2012年10月收治的椎管内麻醉下行剖宫产手术的患者72例，按入院随机号分为两组，每组各36例，观察组胎儿娩出立即给予静脉注射盐酸右美托咪定； 对照组给予静脉注射曲马多。结果：麻醉前、麻醉后及手术结束后两组患者MAP、SPO2、HR、CVP各观察指标比较均无统计学意义（P＞0.05）；麻醉恢复期，两组产妇寒战发生率差异无统计学意义（P＞0.05）；对照组不良反应发生率明显高于对照组，差异显著（P＜0.05）。结论：右美托咪定预防椎管内麻醉期寒战与曲马多相当，但安全性明显提高，可作为预防椎管内麻醉期寒战的首先药物。 【关键词】右美托咪定；曲马多寒战Clinical analysis of dexmedetomidine the prevention spinal anesthesia cesarean section patients shivering Abstract Objective: To evaluate the dexmedetomidine prevention clinical efficacy of spinal anesthesia during cesarean delivery shivering reaction. Method: Admitted to our hospital from November 2011 to October 2012 spinal anesthesia for cesarean delivery 72 patients, divided into two groups according to the hospitalized random number, 36 cases in each group, the observation group fetus immediate intravenous control group received intravenous tramadol injection hydrochloric dexmedetomidine; Results: Before anesthesia, after anesthesia and surgery after two groups of patients MAP, SPO2, HR, CVP various observational indicators were not statistically significant P 0.05 ;Recovery from anesthesia, the two sets of maternal shivering difference in the incidence was not statistically significant P 0.05 ; the control group was significantly higher incidence of adverse reactions, the difference was significant P 0.05 . Conclusion: Dexmedetomidine for prevention of the spinal anesthesia shivering tramadol considerable, but safety is significantly improved as the first drug for prevention of spinal anesthesia shivering. Keyword：Dexmedetomidine；Tramadol；shivering 寒战是临床椎管内麻醉恢复期间的常见并发症，发生率较高，对患者的恢复及生活质量均产生不良影响。曲马多是目前临床应用较多的预防寒战的有效药物，但由于曲马多对体温影响较大，且较易发生恶心、呕吐等胃肠道不良反应，因而，临床应用受到了一定的局限。近年来，盐酸右美托咪定在预防剖宫产患者椎管内麻醉期间寒战反应有较好的疗效。本研究对我院2011年11月至2012年10月收治的椎管内麻醉下行剖宫产手术的患者分别给予曲马多和右美托咪定预防麻醉恢复期间的寒战反应，现将其临床结果报道如下： 1 临床资料与方法 1.1 临床资料 选取我院2011年11月至2012年10月收治的椎管内麻醉下行剖宫产手术的72例患者，年龄在24～41岁之间，平均年龄为（30.37±3.22）岁，体重48～95kg，平均（66.41±6.81）kg；其中初产妇64例