孕期铅暴露与脐血铅负荷水平研究.docVIP

　　【摘要】 目的 观察孕期低水平铅暴露与脐血铅相关性，提出微环境自我保护的重要意义，了解被动吸烟、居室近期装修、燃煤、住地环境污染因素对血铅的影响。方法 对140例孕妇进行问卷调查，采用美国ESA公司Lead Care系统对140例新生儿进行脐血铅测定。结果 140例脐血铅水平ˉx 21.04μg/L，SD 11.73μg/L，范围0.1～73μg/L。140例脐血铅按出生体重的不同、母亲有无吸烟史、母亲文化水平的高低、家庭有无燃煤以及母亲职业有无铅暴露分为5组，将每一组间的血铅水平比较，显示每一组间血铅水平差异无显著性（P值分别为0.487，0.24，0.063，0.63，0.85，均 0.05）。本组孕妇被动吸烟者占37.86%，2年内家庭新装修占22.1%，燃煤用煤占36.42%。结论 （1）本组血铅无一例为零。（2）孕期铅暴露可使脐血铅负荷水平增高。（3）Lead Care系统是一种快速、简便的血铅测定仪。 　　关键词 孕妇 血铅 脐血 　　The study on lead exposure in pregnancy and the umbilical cord blood lead level Song Li，Xi Weiping，Yang Jianping，et al. Department of obstetrics and Gynecology，Changzhi Medical college of Shanxi，Changzhi046000. 【Abstract】 Objective The study aimed at investigating the correlation between lower level lead exposurein pregˉnancy and umbilical cord blood lead level，putting forward the significance of protecting microenvironment by ourselves.At the same time we also realized some factors which affected blood lead level.The factors were passive smoking，resiˉdential fitment recently，blazing coal，pollution of environment and so on.Methods The140pregnant women were inˉvestigated with questionnaires and the140newborn infants were implemented laboratory check about umbilical cord blood lead level determination by using American ESA Company Lead Care System.Results The umbilical cord blood lead level isˉx 21.04μg/L，SD 11.73μg/L，ranged from0.1to73μg/L.According to different birth weight，mother smoking，maternal level of education，household blazing coal and maternal occupation（lead exposure）we classified140umbilical cord blood lead level as five different groups respectively.There was not significant difference of blood lead levˉel in each group（P 0.487，0.24，0.063，0.63，0.85， 0.05）The percent of the pregnant women who belonged to passive smoking was37.86%，the percent of the residential fitmcnt in two years was22.1%and the percent of the blazˉing coal was36.24%.Conclusion （1）Among all cases the blood lead level determination exceeded zero.（2）Lead exˉposure i