AtrialfibrillationinChina.pptVIP

Higher Mortality Rate In Patients With AF The epidemiology of atrial fibrillation ATRIAL FIBRILLATION AND STROKE Thrombembolic stroke High Incidence Multi-focal and severe Prone to hemorrhage High mortality The Framingham Study: Attributable Risk of Stroke Prevalence of AF in different countries Atrial Fibrillation Demographics by Age Prevalence of AF is increasing in USA Percent of Hospitalization in Patients with AF Is Increasing in China Prevalence of AF in China and other countries Prevalence of Stroke in Chinese Patients with AF Prevalence of Stroke in Patients with None Valve AF Stratified by Age Risk Factors for Stroke in Chinese with Non Vascular AF: A Case-control Study AF Investigators: Meta-analysisWarfarin for Stroke Prevention Antiplatetet and Anticoagulation showed Significant Lower Stroke in Chinese Hospitalized Patients with AF Prevalence of Antiplatetet and Anticoagulation in Chinese Hospitalized Patients with AF Prevalence of Antiplatelet and Anticoagulation in Patients with AF in Chinese Natural Population Is Warfarin Better than Aspirin? If So What is the Optimal INR Is Warfarin Better than Aspirin? If So What is the Optimal INR? Results— Baseline Characteristics Results --Treatments Received and Concomitant Medications ResultsPrimary Endpoints ResultsAll-Cause Death Results Total Embolic Events Results  Secondary Endpoints Results Adverse Events-- Hemorrhage Results: combined end points Conclusions Compared to aspirin, adjusted-dosed warfarin INR 2.0-3.0 can significantly reduce: -- primary endpoints by 44% 56% -- thromboembolism events by 52% -- combined endpoints by 36%39% For Chinese NVAF patients, most of which 63.5% have at least one risk factor, warfarin is more effective than aspirin 150-160mg Warfarin is associated with increased risk of hemorrhage. Is Warfarin Better than Aspirin? If So What is the Optimal INR? Distribution of 3482 INRs during follow-up Thromboembolic event in Warfarin Hemorrhage