AntiprotozoalDrugs.pptVIP

Antiparasitic Drugs Fen-Fei Gao Overview Antimalarial drugs Anti-amebiasis drugs and Anti-trichomoniasis drugs Anti-schistosomiasis drugs and Anti-filariasis drugs Anthelmintic drugs Malaria(疟疾) Malaria is caused by plasmodium (疟原虫) whose sporozoites(子孢子) was inoculated to initiate human infection by anopheline mosquito(按蚊). Four species of plasmodium cause human malaria: Plasmodium falciparum (恶性疟) → responsible for nearly all serious complications(并发症) and deaths. P vivax (间日疟) P malariae (三日疟) P ovale(卵圆形疟) → seldom Parasite(寄生虫) Life Cycle Asexual stage in human: Primary exoerythrocyti